Blood and Roses is set in the troubled era of the British Civil War. Simon, a Puritan of noble birth, joins his father to fight on the side of the Parliamentarians for religious freedom in England, but becomes disillusioned when the New Model Army goes to the extreme of executing the king. Will he decide to join those who have emigrated to New England? Nell, a servant at Haresby Hall, runs away to find her brother who is fighting for the Royalists. Will she find him alive? Will she find a husband who can live with her free spirit?

Eleanor is the rich heiress of Haresby Hall. A staunch Royalist, when her father is killed in the war, she is left to manage the estate on her own in a region where the Parliamentarians are gaining power. Duncan, also from a well-to-do family, comes to her aid, but will he and Haresby Hall be lost to her?

The lives of the four intertwine as they seek for truth and love in a nation torn apart by religious and political power mongering and they are confronted with issues in their relationships with one another and with God.